Metabolic risk factors in nondiabetic adolescents with glomerular hyperfiltration
نویسندگان
چکیده
منابع مشابه
Glomerular hyperfiltration: a new marker of metabolic risk.
Chronic kidney disease coexists with metabolic syndrome and this relationship may be apparent before overt manifestations of cardiovascular disease. To investigate early stages of the natural history of associations between renal function and metabolic syndrome, we phenotyped 1572 young (mean age=18.4 years), apparently healthy men for metabolic risk factors and estimated their creatinine clear...
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S ickle cell disease (SCD) is a monogenetic, chronic anemia syndrome that is caused by a point mutation in the -globin gene and affects approximately 100,000 individuals in the United States. Approximately 4 to 5% of these individuals have or will develop stage 5 chronic kidney disease (CKD), and 0.11% of patients who are on long-term maintenance renal replacement therapy have SCD-associated ne...
متن کاملGlomerular hyperfiltration in hypertensive African Americans.
The incidence of end-stage renal disease attributable to hypertension is 5-fold greater in African Americans than in whites. To determine whether glomerular hyperfiltration is an antecedent to renal failure, we compared responses of renal blood flow and glomerular filtration rate to graded infusions of norepinephrine (0. 01, 0.025, and 0.05 microg. kg(-1). min(-1) for 30 minutes each) in 29 Afr...
متن کاملRelative glomerular hyperfiltration in primary aldosteronism.
Experimental and clinical data suggest that primary aldosteronism (PA) may be associated with cardiovascular hypertrophy and fibrosis, in part independent of the BP level. Whether PA may also result in specific deleterious effects on the kidneys was less studied. In 25 patients with tumoral PA, renal studies (urinary excretion of proteins, GFR, and effective renal plasma flow [ERPF], as clearan...
متن کاملGlomerular hyperfiltration in prediabetes and prehypertension.
BACKGROUND This study aimed to investigate the associations of hyperfiltration and hypofiltration with prediabetes and prehypertension. METHODS The study subjects included 99 140 people aged 20-89 years who underwent health checkups in Aichi Prefecture, Japan. The prevalence of hyperfiltration [estimated glomerular filtration rate (eGFR) above the age-/sex-specific 95th percentile] and hypofi...
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ژورنال
عنوان ژورنال: Nephrology Dialysis Transplantation
سال: 2016
ISSN: 0931-0509,1460-2385
DOI: 10.1093/ndt/gfw231